Fuel Your Focus: An Anti-Inflammatory Diet Plan for Optimal Brain Health
Have you ever experienced temporary brain fog? Perhaps you forgot a doctor’s appointment or suddenly found it difficult to complete simple paperwork—symptoms that may improve with an anti-inflammatory diet.
To a certain degree, cognitive decline is part of the aging process, and occasional brain fog can become more common as we enter middle age. Over 28% of participants in a recent study reported that they sometimes experience confusion or forgetfulness, feel mentally exhausted, or struggle to concentrate or follow conversations.
Prolonged or persistent inflammation within the body could be the culprit. But there’s evidence that an anti-inflammatory diet plan may help relieve symptoms of brain fog.
The Tenets of an Anti-Inflammatory Diet Plan
Chronic inflammation within the body has been linked to a range of disorders, including heart disease and an increased risk of cancer. But it’s important to know that inflammation, even at low levels, also affects the brain, causing it to function suboptimally.
We can help reduce inflammation by getting proper sleep and adequate exercise, managing stress sensibly, and following an effective anti-inflammatory diet plan.
Here are some careful but simple measures you can take to potentially reduce inflammation and slow down long-range cognitive decline:
- Limit your consumption of fried foods and fast food, which absorb inflammatory oils from the cooking process.
- Be mindful of added sugars in the foods you consume. Regulate your intake of processed foods, especially those high in added sugar.
- Be judicious about how often you dine out. Regardless of the restaurant, you have little control over how your food is prepared.
- Taper back or avoid alcohol, another inflammatory agent.
Anti-Inflammatory Foods to Focus On
Making lasting dietary changes that benefit your brain health shouldn’t be a chore.
The Mediterranean diet pyramid depicts a simple, anti-inflammatory way of eating that supports both brain and heart health. The bottom of the pyramid includes foods that should compose the majority of your diet, while the top points out the foods to consume infrequently or in moderation.
The Mediterranean diet’s anti-inflammatory superstars include:
- Plant-based foods — fruits and vegetables, beans and legumes, nuts and seeds
- Whole grains (for those not gluten-sensitive or -intolerant)
- Fatty fish, nuts, and seeds rich in omega-3 healthy fats
In certain studies, participants reported feeling less brain fog and experiencing greater energy when they tried intermittent fasting. However, others feel increased brain fog and a dip in energy if they restrict calories in the morning hours.
If you experience occasional brain fog, try a couple of dry runs to see if intermittent fasting helps clear it.
How to Create an Anti-Inflammatory Diet Plan
To create an anti-inflammatory diet plan, use the Mediterranean diet as a guide.
Small, easy hacks like these can help you progressively add brain-healthy, energy-boosting foods to your plate:
- Gradually include more plant-based foods in your daily diet. For example, consider adding beans to your chili or nuts to your yogurt.
- Incorporate a range of colorful, antioxidant-rich foods into your diet, such as peppers, berries, and leafy greens. The more colors on your plate, the better.
- Add fish to your plate once a week. If you don’t like fish or can’t eat it, consider taking an omega-3 supplement to get the benefit of those healthy fats.
- Add flaxseed or chia seeds to your oatmeal or yogurt.
- Spread avocado on your sandwich or burger.
Holistic Support for Your Brain
Tweaking your diet to manage inflammation is a great way to support good brain health and clear a foggy brain.
To give your brain its best chance at sustained health, your anti-inflammatory diet plan must go hand-in-hand with proper exercise, adequate sleep, and careful stress management.
Your Signature Healthcare team is standing by to help with every aspect of your longevity journey. Let’s get you started.

Natalie Mokari, RDN LDN
Natalie Mokari is a skilled dietitian with a Bachelor of Science in Food Science and Human Nutrition from Clemson University, complemented by a dietetic internship in Charlotte. Her expertise spans outpatient clinical nutrition, private counseling, corporate wellness, and school food service, emphasizing a non-diet approach and mindful eating. Outside the clinic, she relishes trying new recipes, outdoor activities, traveling, and exploring Charlotte with her husband and dog.